DISTINCTLY DIFFERENT

BECAUSE OF OUR PARENTS

ARCHIE

ARCHIE: Up and Coming Male - Pictured at 6 weeks of age

PARENTS: BO & KENZIE

DOB: 6/2/19

BO - Father

Bo's Mom

Excellent OFA Hips

Bo's Dad

Excellent OFA Hips

BO IS COMPLETELY CLEAR

OF ALL OF THE FOLLOWING

Genetically based Diseases!

Total of over 170 diseases

Von Willebrand Disease Type I (VWF) BLOOD


Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in Poodle (Standard)s, Poodle (Small)s, but not Lakeshore's Intricate Details.

Congenital Macrothrombocytopenia (TUBB1 Exon 1, Cavalier King Charles Spaniel Variant) BLOOD


This is a benign disorder of platelet production that leads to abnormally large, sparse platelets. Affected dogs typically do not suffer any ill effects from the size or …

Seen in Poodle (Standard)s, Poodle (Small)s, but not Lakeshore's Intricate Details.

Progressive Retinal Atrophy - prcd Progressive rod-cone degeneration (PRCD Exon 1) EYES


This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Poodle (Standard)s, Poodle (Small)s, but not Lakeshore's Intricate Details.

GM2 Gangliosidosis (HEXB, Poodle Variant) MULTISYSTEM


An early onset form of lysosomal storage disease, this can cause affected dogs to display neurologic signs as puppies or young adults. These include partial or total visi…

Seen in Poodle (Standard)s, Poodle (Small)s, but not Lakeshore's Intricate Details.

Degenerative Myelopathy (SOD1A) BRAIN AND SPINAL CORD


A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in Poodle (Standard)s, Poodle (Small)s, but not Lakeshore's Intricate Details.

Neonatal Encephalopathy with Seizures (NEWS) (ATF2) BRAIN AND SPINAL CORD


A neurologic disease of puppies, affected puppies are often smaller than their unaffected littermates and require intensive nursing care. Without this extra support, pupp…

Seen in Poodle (Standard)s, Poodle (Small)s, but not Lakeshore's Intricate Details.

Osteochondrodysplasia, Skeletal Dwarfism (SLC13A1) SKELETAL


A form of skeletal dwarfism, this causes affected dogs to have abnormally short legs but a normal sized body due to abnormal fetal skeletal maturation. As a fetus, most o…

Seen in Poodle (Standard)s, Poodle (Small)s, but not Lakeshore's Intricate Details.

MDR1 Drug Sensitivity (MDR1)

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutations in the MDR1 gene. Symptoms can range from vomiting and diarrhea to lethargy, seizures, or coma. MDR1 mutations are particularly common in herding breeds including Australian Shepherds, Collies, and Border Collies, though many other dog breeds are affected. Please note that the dosage of problem drugs in commercially available heartworm, flea, and tick preventatives should not cause symptoms in MDR1 dogs.

ALL GENETICALLY BASED BLOOD ISSUES

ALL GENETICALLY BASED HORMONE ISSUES

ALL IMMUNE CONDITIONS TESTED FOR

ALL EYE CONDITIONS TESTED FOR

Bo is clear of all the Kidney and Bladder conditions that Embark tests for.

Bo is clear of all the Multisystem conditions that Embark tests for.

Bo is clear of all the Other Systems conditions that Embark tests for.

Bo is clear of all the Brain and Spinal Cord conditions that Embark tests for.

Bo is clear of all the Heart conditions that Embark tests for.

Bo is clear of all the Muscular conditions that Embark tests for.

Bo is clear of all the Metabolic conditions that Embark tests for.

Bo is clear of all the Gastrointestinal conditions that Embark tests for.

Bo is clear of all the Neuromuscular conditions that Embark tests for.

Bo is clear of all the Skin & Connective Tissues conditions that Embark tests for

Bo is clear of all the Skeletal conditions that Embark tests for.

Kenzie - Mother

Kenzie's Dad

Hips, Eyes, DM, NE, VWD

Kenzie's Mom

KENZIE IS COMPLETELY CLEAR FOR ALL OF THE FOLLOWING GENETIC DISEASES

Kenzie tested CLEAR for all these conditions:

Clinical

  • MDR1 Drug Sensitivity (MDR1) (Chromosome 14)

Hematologic (Blood)

  • P2Y12 Receptor Platelet Disorder (P2RY12) (Chromosome 23)

  • Factor IX Deficiency, Hemophilia B (F9 Exon 7, Terrier Variant) (Chromosome X)

  • Factor IX Deficiency, Hemophilia B (F9 Exon 7, Rhodesian Ridgeback Variant) (Chromosome X)

  • Factor VII Deficiency (F7 Exon 5) (Chromosome 22)

  • Factor VIII Deficiency, Hemophilia A (F8 Exon 10, Boxer Variant) (Chromosome X)

  • Factor VIII Deficiency, Hemophilia A (F8 Exon 11, Shepherd Variant 1) (Chromosome X)

  • Factor VIII Deficiency, Hemophilia A (F8 Exon 1, Shepherd Variant 2) (Chromosome X)

  • Thrombopathia (RASGRP2 Exon 5, Basset Hound Variant) (Chromosome 18)

  • Thrombopathia (RASGRP2 Exon 8) (Chromosome 18)

  • Thrombopathia (RASGRP2 Exon 5, American Eskimo Dog Variant) (Chromosome 18)

  • Von Willebrand Disease Type III (VWF Exon 4) (Chromosome 27)

  • Von Willebrand Disease Type I (VWF) (Chromosome 27)

  • Von Willebrand Disease Type II (VWF) (Chromosome 27)

  • Canine Leukocyte Adhesion Deficiency Type III (LAD3) (FERMT3) (Chromosome 18)

  • Congenital Macrothrombocytopenia (TUBB1 Exon 1, Cavalier King Charles Spaniel Variant) (Chromosome 24)

  • Canine Elliptocytosis (SPTB Exon 30) (Chromosome 8)

  • Cyclic Neutropenia, Gray Collie Syndrome (AP3B1 Exon 20) (Chromosome 31)

  • Glanzmann's Thrombasthenia Type I (ITGA2B Exon 12) (Chromosome 9)

  • May-Hegglin Anomaly (MYH9) (Chromosome 10)

  • Prekallikrein Deficiency (KLKB1 Exon 8) (Chromosome 16)

  • Pyruvate Kinase Deficiency (PKLR Exon 5) (Chromosome 7)

  • Pyruvate Kinase Deficiency (PKLR Exon 7 Labrador Variant) (Chromosome 7)

  • Pyruvate Kinase Deficiency (PKLR Exon 7 Pug Variant) (Chromosome 7)

  • Pyruvate Kinase Deficiency (PKLR Exon 7 Beagle Variant) (Chromosome 7)

  • Pyruvate Kinase Deficiency (PKLR Exon 10) (Chromosome 7)

  • Trapped Neutrophil Syndrome (VPS13B) (Chromosome 13)

  • Ligneous Membranitis (PLG) (Chromosome 1)

Endocrine (Hormones)

  • Congenital Hypothyroidism (TPO, Tenterfield Terrier Variant) (Chromosome 17)

Immunologic (Immune)

  • Complement 3 (C3) deficiency (C3) (Chromosome 20)

  • Severe Combined Immunodeficiency (PRKDC) (Chromosome 29)

  • Severe Combined Immunodeficiency (RAG1) (Chromosome 18)

  • X-linked Severe Combined Immunodeficiency (IL2RG Variant 1) (Chromosome X)

  • X-linked Severe Combined Immunodeficiency (IL2RG Variant 2) (Chromosome X)

Ophthalmologic (Eyes)

  • Progressive Retinal Atrophy - rcd1 Rod-cone dysplasia, rcd1 (PDE6B Exon 21 Irish Setter Variant) (Chromosome 3)

  • Progressive Retinal Atrophy Rod-cone dysplasia, rcd1a (PDE6B Exon 21 Sloughi Variant) (Chromosome 3)

  • Progressive Retinal Atrophy - rcd3 Rod-cone dysplasia, rcd3 (PDE6A) (Chromosome 4)

  • Progressive Retinal Atrophy - CNGA (CNGA1 Exon 9) (Chromosome 13)

  • Progressive Retinal Atrophy - prcd Progressive rod-cone degeneration (PRCD Exon 1) (Chromosome 9)

  • Progressive Retinal Atrophy (CNGB1) (Chromosome 2)

  • Progressive Retinal Atrophy (SAG) (Chromosome 25)

  • Golden Retriever Progressive Retinal Atrophy 1 (SLC4A3) (Chromosome 37)

  • Golden Retriever Progressive Retinal Atrophy 2 (TTC8) (Chromosome 8)

  • Progressive Retinal Atrophy - crd1 (PDE6B) (Chromosome 3)

  • Progressive Retinal Atrophy - crd2 (IQCB1) (Chromosome 33)

  • Progressive Retinal Atrophy - crd4/cord1 (RPGRIP1) (Chromosome 15)

  • Collie Eye Anomaly, Choroidal Hypoplasia (NHEJ1) (Chromosome 37)

  • Achromatopsia (CNGA3 Exon 7 German Shepherd Variant) (Chromosome 10)

  • Achromatopsia (CNGA3 Exon 7 Labrador Retriever Variant) (Chromosome 10)

  • Autosomal Dominant Progressive Retinal Atrophy (RHO) (Chromosome 20)

  • Canine Multifocal Retinopathy cmr1 (BEST1 Exon 2) (Chromosome 18)

  • Canine Multifocal Retinopathy cmr2 (BEST1 Exon 5) (Chromosome 18)

  • Canine Multifocal Retinopathy cmr3 (BEST1 Exon 10 Deletion) (Chromosome 18)

  • Canine Multifocal Retinopathy cmr3 (BEST1 Exon 10 SNP) (Chromosome 18)

  • Glaucoma Primary Open Angle Glaucoma (ADAMTS10 Exon 9) (Chromosome 20)

  • Glaucoma Primary Open Angle Glaucoma (ADAMTS10 Exon 17) (Chromosome 20)

  • Glaucoma Primary Open Angle Glaucoma (ADAMTS17 Exon 11) (Chromosome 3)

  • Glaucoma Primary Open Angle Glaucoma (ADAMTS17 Exon 2) (Chromosome 3)

  • Hereditary Cataracts, Early-Onset Cataracts, Juvenile Cataracts (HSF4 Exon 9 Shepherd Variant) (Chromosome 5)

  • Primary Lens Luxation (ADAMTS17) (Chromosome 3)

  • Congenital stationary night blindness (RPE65) (Chromosome 6)

  • Macular Corneal Dystrophy (MCD) (CHST6) (Chromosome 5)

Urinary (Kidney and Bladder)

  • 2,8-Dihydroxyadenine (2,8-DHA) Urolithiasis (APRT) (Chromosome 5)

  • Cystinuria Type I-A (SLC3A1) (Chromosome 10)

  • Cystinuria Type II-A (SLC3A1) (Chromosome 10)

  • Cystinuria Type I-A (SLC7A9) (Chromosome 1)

  • Hyperuricosuria and Hyperuricemia or Urolithiasis (SLC2A9) (Chromosome 3)

  • Polycystic Kidney Disease (PKD1) (Chromosome 6)

  • Primary Hyperoxaluria (AGXT) (Chromosome 25)

  • Protein Losing Nephropathy (NPHS1) (Chromosome 1)

  • X-Linked Hereditary Nephropathy (Samoyed Variant 2) (COL4A5 Exon 35) (Chromosome X)

  • Autosomal Recessive Hereditary Nephropathy, Familial Nephropathy (COL4A4 Exon 3) (Chromosome 25)

Multisystem

  • Primary Ciliary Dyskinesia (CCDC39 Exon 3) (Chromosome 34)

  • Congenital Keratoconjunctivitis Sicca and Ichthyosiform Dermatosis (CKCSID), Dry Eye Curly Coat Syndrome (FAM83H Exon 5) (Chromosome 13)

  • X-linked Ectodermal Dysplasia, Anhidrotic Ectodermal Dysplasia (EDA Intron 8) (Chromosome X)

  • Renal Cystadenocarcinoma and Nodular Dermatofibrosis (RCND) (FLCN Exon 7) (Chromosome 5)

  • Canine Fucosidosis (FUCA1) (Chromosome 2)

  • Glycogen Storage Disease Type II, Pompe's Disease (GAA) (Chromosome 9)

  • Glycogen Storage Disease Type Ia, Von Gierke Disease (G6PC) (Chromosome 9)

  • Glycogen Storage Disease Type IIIa (GSD IIIa) (AGL) (Chromosome 6)

  • Mucopolysaccharidosis Type I (IDUA) (Chromosome 3)

  • Mucopolysaccharidosis Type IIIA, Sanfilippo Syndrome Type A (SGSH Exon 6 Variant 1) (Chromosome 9)

  • Mucopolysaccharidosis Type IIIA, Sanfilippo Syndrome Type A (SGSH Exon 6 Variant 2) (Chromosome 9)

  • Mucopolysaccharidosis Type VII, Sly Syndrome (GUSB Exon 5) (Chromosome 6)

  • Mucopolysaccharidosis Type VII, Sly Syndrome (GUSB Exon 3) (Chromosome 6)

  • Glycogen storage disease Type VII, Phosphofructokinase deficiency (PFKM Whippet and English Springer Spaniel Variant) (Chromosome 27)

  • Glycogen storage disease Type VII, Phosphofructokinase deficiency (PFKM Wachtelhund Variant) (Chromosome 27)

  • Lagotto Storage Disease (ATG4D) (Chromosome 20)

  • Neuronal Ceroid Lipofuscinosis 1 (PPT1 Exon 8) (Chromosome 15)

  • Neuronal Ceroid Lipofuscinosis 2 (TPP1 Exon 4) (Chromosome 21)

  • Neuronal Ceroid Lipofuscinosis 1, Cerebellar Ataxia - NCL-A (ARSG Exon 2) (Chromosome 9)

  • Neuronal Ceroid Lipofuscinosis 1 (CLN5 Border Collie Variant) (Chromosome 22)

  • Neuronal Ceroid Lipofuscinosis 6 (CLN6 Exon 7) (Chromosome 30)

  • Neuronal Ceroid Lipofuscinosis 8 (CLN8 English Setter Variant) (Chromosome 37)

  • Neuronal Ceroid Lipofuscinosis (MFSD8) (Chromosome 19)

  • Neuronal Ceroid Lipofuscinosis (CLN8 Australian Shepherd Variant) (Chromosome 37)

  • Neuronal Ceroid Lipofuscinosis 10 (CTSD Exon 5) (Chromosome 18)

  • Neuronal Ceroid Lipofuscinosis (CLN5 Golden Retriever Variant) (Chromosome 22)

  • Adult-Onset Neuronal Ceroid Lipofuscinosis (ATP13A2) (Chromosome 2)

  • GM1 Gangliosidosis (GLB1 Exon 15 Shiba Inu Variant) (Chromosome 23)

  • GM1 Gangliosidosis (GLB1 Exon 15 Alaskan Husky Variant) (Chromosome 23)

  • GM1 Gangliosidosis (GLB1 Exon 2) (Chromosome 23)

  • GM2 Gangliosidosis (HEXB, Poodle Variant) (Chromosome 2)

  • GM2 Gangliosidosis (HEXA) (Chromosome 30)

  • Globoid Cell Leukodystrophy, Krabbe disease (GALC Exon 5) (Chromosome 8)

Other Systems

  • Autosomal Recessive Amelogenesis Imperfecta (Italian Greyhound Variant) (Chromosome 13)

  • Persistent Mullerian Duct Syndrome (AMHR2) (Chromosome 27)

  • Deafness and Vestibular Syndrome of Dobermans (DVDob, DINGS) (Chromosome 21)

  • Shar-Pei Autoinflammatory Disease (SPAID, Shar-Pei Fever) (MTBP) (Chromosome 13)

Neurologic (Brain and Spinal Cord)

  • Alaskan Husky Encephalopathy, Subacute Necrotizing Encephalomyelopathy (SLC19A3) (Chromosome 25)

  • Alexander Disease (GFAP) (Chromosome 9)

  • Cerebellar Abiotrophy, Neonatal Cerebellar Cortical Degeneration (SPTBN2) (Chromosome 18)

  • Cerebellar Ataxia, Progressive Early-Onset Cerebellar Ataxia (SEL1L) (Chromosome 8)

  • Cerebellar Hypoplasia (VLDLR) (Chromosome 1)

  • Spinocerebellar Ataxia, Late-Onset Ataxia (CAPN1) (Chromosome 18)

  • Spinocerebellar Ataxia with Myokymia and/or Seizures (KCNJ10) (Chromosome 38)

  • Benign Familial Juvenile Epilepsy, Remitting Focal Epilepsy (LGI2) (Chromosome 3)

  • Degenerative Myelopathy (SOD1A) (Chromosome 31)

  • Fetal-Onset Neonatal Neuroaxonal Dystrophy (MFN2) (Chromosome 2)

  • Hypomyelination and Tremors (FNIP2) (Chromosome 15)

  • Shaking Puppy Syndrome, X-linked Generalized Tremor Syndrome (PLP) (Chromosome X)

  • L-2-Hydroxyglutaricaciduria (L2HGDH) (Chromosome 0)

  • Neonatal Encephalopathy with Seizures (NEWS) (ATF2) (Chromosome 36)

  • Polyneuropathy, NDRG1 Greyhound Variant (NDRG1 Exon 15) (Chromosome 13)

  • Polyneuropathy, NDRG1 Malamute Variant (NDRG1 Exon 4) (Chromosome 13)

  • Narcolepsy (HCRTR2 Intron 6) (Chromosome 12)

  • Progressive Neuronal Abiotrophy (Canine Multiple System Degeneration) (SERAC1 Exon 15) (Chromosome 1)

  • Progressive Neuronal Abiotrophy (Canine Multiple System Degeneration) (SERAC1 Exon 4) (Chromosome 1)

  • Juvenile Laryngeal Paralysis and Polyneuropathy, Polyneuropathy with Ocular Abnormalities and Neuronal Vacuolation (POANV) (RAB3GAP1, Rottweiler Variant) (Chromosome 19)

  • Hereditary Sensory Autonomic Neuropathy (HSAN), Acral Mutilation Syndrome (GDNF-AS) (Chromosome 4)

  • Juvenile-Onset Polyneuropathy, Leonberger Polyneuropathy 1 (LPN1, ARHGEF10) (Chromosome 16)

  • Spongy Degeneration with Cerebellar Ataxia 1 (SDCA1), SeSAME/EAST (KCNJ10) (Chromosome 38)

  • Spongy Degeneration with Cerebellar Ataxia 2 (SDCA2) (ATP1B2) (Chromosome 5)

Cardiac (Heart)

  • Dilated Cardiomyopathy (PDK4) (Chromosome 14)

  • Long QT Syndrome (KCNQ1) (Chromosome 18)

Muscular

  • Muscular Dystrophy Cavalier King Charles Spaniel Variant 1 (Chromosome X)

  • Muscular Dystrophy Muscular Dystrophy (DMD Pembroke Welsh Corgi Variant ) (Chromosome X)

  • Muscular Dystrophy Muscular Dystrophy (DMD Golden Retriever Variant) (Chromosome X)

  • Centronuclear Myopathy (PTPLA) (Chromosome 2)

  • Exercise-Induced Collapse (DNM1) (Chromosome 9)

  • Inherited Myopathy of Great Danes (BIN1) (Chromosome 19)

  • Myostatin Deficiency, Bully Whippet Syndrome (MSTN) (Chromosome 37)

  • Myotonia Congenita (CLCN1 Exon 7) (Chromosome 16)

  • Myotonia Congenita (CLCN1 Exon 23) (Chromosome 16)

  • Myotubular Myopathy 1, X-linked Myotubular Myopathy (MTM1) (Chromosome X)

Metabolic

  • Hypocatalasia, Acatalasemia (CAT) (Chromosome 18)

  • Pyruvate Dehydrogenase Deficiency (PDP1) (Chromosome 29)

  • Malignant Hyperthermia (RYR1) (Chromosome 1)

Gastrointestinal

  • Imerslund-Grasbeck Syndrome, Selective Cobalamin Malabsorption (CUBN Exon 53) (Chromosome 2)

  • Imerslund-Grasbeck Syndrome, Selective Cobalamin Malabsorption (CUBN Exon 8) (Chromosome 2)

Neuromuscular

  • Congenital Myasthenic Syndrome (CHAT) (Chromosome 28)

  • Congenital Myasthenic Syndrome (COLQ) (Chromosome 23)

  • Episodic Falling Syndrome (BCAN) (Chromosome 7)

Integument (Skin & Connective Tissues)

  • Dystrophic Epidermolysis Bullosa (COL7A1) (Chromosome 20)

  • Ectodermal Dysplasia, Skin Fragility Syndrome (PKP1) (Chromosome 7)

  • Ichthyosis, Epidermolytic Hyperkeratosis (KRT10) (Chromosome 9)

  • Ichthyosis (PNPLA1) (Chromosome 12)

  • Ichthyosis (SLC27A4) (Chromosome 9)

  • Ichthyosis (NIPAL4) (Chromosome 4)

  • Focal Non-Epidermolytic Palmoplantar Keratoderma, Pachyonychia Congenita (KRT16) (Chromosome 9)

  • Hereditary Footpad Hyperkeratosis (FAM83G) (Chromosome 5)

  • Hereditary Nasal Parakeratosis (SUV39H2) (Chromosome 2)

  • Musladin-Lueke Syndrome (ADAMTSL2) (Chromosome 9)

Skeletal

  • Cleft Lip and/or Cleft Palate (ADAMTS20) (Chromosome 27)

  • Hereditary Vitamin D-Resistant Rickets (VDR) (Chromosome 27)

  • Oculoskeletal Dysplasia 1, Dwarfism-Retinal Dysplasia (COL9A3, Labrador Retriever) (Chromosome 24)

  • Osteogenesis Imperfecta, Brittle Bone Disease (COL1A2) (Chromosome 14)

  • Osteogenesis Imperfecta, Brittle Bone Disease (SERPINH1) (Chromosome 21)

  • Osteogenesis Imperfecta, Brittle Bone Disease (COL1A1) (Chromosome 9)

  • Osteochondrodysplasia, Skeletal Dwarfism (SLC13A1) (Chromosome 14)

  • Skeletal Dysplasia 2 (COL11A2) (Chromosome 12)

  • Craniomandibular Osteopathy (CMO) (SLC37A2) (Chromosome 5)

Kenzie: Hips, elbow, heart, patella

Kenzie's Father: hips, eyes, DM, NE, Vwd

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Call or Text (585) 623-0426

NYS PD #365